VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 98% Sens / 92% Spec / 2% Prevalence

With 98% sensitivity, 92% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 20.0%.

Bayes Theorem: PPV = TP / (TP + FP) = (98% × 2%) / [(98% × 2%) + (8% × 98%)] = 20.0%.
FAQ: What is the PPV when sensitivity is 98%, specificity is 92%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 20.0%, meaning 80.0% of positive results at 2% prevalence are false positives.