VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 96% Sens / 80% Spec / 10% Prevalence

With 96% sensitivity, 80% specificity, and 10% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 34.8%.

Bayes Theorem: PPV = TP / (TP + FP) = (96% × 10%) / [(96% × 10%) + (20% × 90%)] = 34.8%.
FAQ: What is the PPV when sensitivity is 96%, specificity is 80%, and prevalence is 10%?

The Positive Predictive Value (PPV) is 34.8%, meaning 65.2% of positive results at 10% prevalence are false positives.