VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 92% Sens / 96% Spec / 10% Prevalence

With 92% sensitivity, 96% specificity, and 10% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 71.9%.

Bayes Theorem: PPV = TP / (TP + FP) = (92% × 10%) / [(92% × 10%) + (4% × 90%)] = 71.9%.
FAQ: What is the PPV when sensitivity is 92%, specificity is 96%, and prevalence is 10%?

The Positive Predictive Value (PPV) is 71.9%, meaning 28.1% of positive results at 10% prevalence are false positives.