VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 92% Sens / 80% Spec / 2% Prevalence

With 92% sensitivity, 80% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 8.6%.

Bayes Theorem: PPV = TP / (TP + FP) = (92% × 2%) / [(92% × 2%) + (20% × 98%)] = 8.6%.
FAQ: What is the PPV when sensitivity is 92%, specificity is 80%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 8.6%, meaning 91.4% of positive results at 2% prevalence are false positives.