VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 90% Sens / 84% Spec / 2% Prevalence

With 90% sensitivity, 84% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 10.3%.

Bayes Theorem: PPV = TP / (TP + FP) = (90% × 2%) / [(90% × 2%) + (16% × 98%)] = 10.3%.
FAQ: What is the PPV when sensitivity is 90%, specificity is 84%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 10.3%, meaning 89.7% of positive results at 2% prevalence are false positives.