VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 86% Sens / 96% Spec / 10% Prevalence

With 86% sensitivity, 96% specificity, and 10% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 70.5%.

Bayes Theorem: PPV = TP / (TP + FP) = (86% × 10%) / [(86% × 10%) + (4% × 90%)] = 70.5%.
FAQ: What is the PPV when sensitivity is 86%, specificity is 96%, and prevalence is 10%?

The Positive Predictive Value (PPV) is 70.5%, meaning 29.5% of positive results at 10% prevalence are false positives.