VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 86% Sens / 94% Spec / 2% Prevalence

With 86% sensitivity, 94% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 22.6%.

Bayes Theorem: PPV = TP / (TP + FP) = (86% × 2%) / [(86% × 2%) + (6% × 98%)] = 22.6%.
FAQ: What is the PPV when sensitivity is 86%, specificity is 94%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 22.6%, meaning 77.4% of positive results at 2% prevalence are false positives.