VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 84% Sens / 90% Spec / 2% Prevalence

With 84% sensitivity, 90% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 14.6%.

Bayes Theorem: PPV = TP / (TP + FP) = (84% × 2%) / [(84% × 2%) + (10% × 98%)] = 14.6%.
FAQ: What is the PPV when sensitivity is 84%, specificity is 90%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 14.6%, meaning 85.4% of positive results at 2% prevalence are false positives.