VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING
Bayesian Positive Predictive Value: 84% Sens / 90% Spec / 10% Prevalence
With 84% sensitivity, 90% specificity, and 10% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 48.3%.
Bayes Theorem: PPV = TP / (TP + FP) = (84% × 10%) / [(84% × 10%) + (10% × 90%)] = 48.3%.
FAQ: What is the PPV when sensitivity is 84%, specificity is 90%, and prevalence is 10%?
The Positive Predictive Value (PPV) is 48.3%, meaning 51.7% of positive results at 10% prevalence are false positives.