VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 84% Sens / 80% Spec / 2% Prevalence

With 84% sensitivity, 80% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 7.9%.

Bayes Theorem: PPV = TP / (TP + FP) = (84% × 2%) / [(84% × 2%) + (20% × 98%)] = 7.9%.
FAQ: What is the PPV when sensitivity is 84%, specificity is 80%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 7.9%, meaning 92.1% of positive results at 2% prevalence are false positives.