VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 84% Sens / 80% Spec / 10% Prevalence

With 84% sensitivity, 80% specificity, and 10% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 31.8%.

Bayes Theorem: PPV = TP / (TP + FP) = (84% × 10%) / [(84% × 10%) + (20% × 90%)] = 31.8%.
FAQ: What is the PPV when sensitivity is 84%, specificity is 80%, and prevalence is 10%?

The Positive Predictive Value (PPV) is 31.8%, meaning 68.2% of positive results at 10% prevalence are false positives.