VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 82% Sens / 94% Spec / 2% Prevalence

With 82% sensitivity, 94% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 21.8%.

Bayes Theorem: PPV = TP / (TP + FP) = (82% × 2%) / [(82% × 2%) + (6% × 98%)] = 21.8%.
FAQ: What is the PPV when sensitivity is 82%, specificity is 94%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 21.8%, meaning 78.2% of positive results at 2% prevalence are false positives.