VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 80% Sens / 90% Spec / 2% Prevalence

With 80% sensitivity, 90% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 14.0%.

Bayes Theorem: PPV = TP / (TP + FP) = (80% × 2%) / [(80% × 2%) + (10% × 98%)] = 14.0%.
FAQ: What is the PPV when sensitivity is 80%, specificity is 90%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 14.0%, meaning 86.0% of positive results at 2% prevalence are false positives.