VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 80% Sens / 82% Spec / 2% Prevalence

With 80% sensitivity, 82% specificity, and 2% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 8.3%.

Bayes Theorem: PPV = TP / (TP + FP) = (80% × 2%) / [(80% × 2%) + (18% × 98%)] = 8.3%.
FAQ: What is the PPV when sensitivity is 80%, specificity is 82%, and prevalence is 2%?

The Positive Predictive Value (PPV) is 8.3%, meaning 91.7% of positive results at 2% prevalence are false positives.