VITAL DX v4.0 • VERIFIED QUANTITATIVE BRIEFING

Bayesian Positive Predictive Value: 80% Sens / 82% Spec / 10% Prevalence

With 80% sensitivity, 82% specificity, and 10% disease prevalence, the Positive Predictive Value (PPV) of a positive test is 33.1%.

Bayes Theorem: PPV = TP / (TP + FP) = (80% × 10%) / [(80% × 10%) + (18% × 90%)] = 33.1%.
FAQ: What is the PPV when sensitivity is 80%, specificity is 82%, and prevalence is 10%?

The Positive Predictive Value (PPV) is 33.1%, meaning 66.9% of positive results at 10% prevalence are false positives.